Multimodal Validation Pipeline Report
| Subject: | sub-009 | Session: | ses-001 |
| Task: | fingertapping | Timestamp: | 2026-01-16T04:53:58.752265 |
Software Versions
- python: 3.11.14
- mne: 1.9.0
- numpy: 2.2.6
- scipy: 1.15.3
Experiment Quality Assurance
Recording duration and trial count validation for EEG and fNIRS modalities.
Recording Duration
| Modality | Duration (s) | Status |
|---|---|---|
| EEG | 1145.5s | â |
| fNIRS | 1145.5s | â |
Valid Trials
| Modality | Valid Trials | Expected Trials | Percentage |
|---|---|---|---|
| EEG | 24 | 24 | 100.0% |
| fNIRS | 24 | 24 | 100.0% |
EEG Channel Quality (Raw Data Metrics)
| Channel | Amplitude Range (ÂĩV) | Std Dev (ÂĩV) | Mean Correlation |
|---|---|---|---|
| Fp1 | 2.01 | 0.34 | 0.689 |
| Fz | 2.17 | 0.50 | 0.678 |
| F3 | 0.84 | 0.09 | 0.136 |
| F7 | 2.62 | 0.23 | 0.270 |
| F9 | 1.67 | 0.25 | -0.504 |
| FC5 | 1.34 | 0.21 | 0.685 |
| FC1 | 3.30 | 0.79 | 0.666 |
| C3 | 2.72 | 0.59 | 0.683 |
| T7 | 1.18 | 0.18 | 0.702 |
| CP1 | 1.09 | 0.16 | 0.636 |
| Pz | 409.43 | 26.57 | -0.334 |
| P3 | 3.39 | 0.82 | 0.668 |
| P7 | 2.68 | 0.59 | 0.684 |
| P9 | 2.56 | 0.52 | 0.678 |
| O1 | 1.92 | 0.41 | 0.690 |
| Oz | 3.11 | 0.66 | 0.678 |
| O2 | 1.88 | 0.34 | 0.699 |
| P10 | 2.78 | 0.63 | 0.684 |
| P8 | 2.42 | 0.54 | 0.687 |
| P4 | 1.96 | 0.39 | 0.698 |
| CP2 | 2.69 | 0.59 | 0.683 |
| T8 | 86.43 | 9.06 | -0.426 |
| C4 | 3.50 | 0.84 | 0.667 |
| Cz | 2.30 | 0.50 | 0.677 |
| FC2 | 2.68 | 0.61 | 0.680 |
| FC6 | 0.91 | 0.11 | 0.130 |
| F10 | 1.30 | 0.17 | 0.661 |
| F8 | 1.42 | 0.21 | 0.699 |
| F4 | 2.16 | 0.43 | 0.684 |
| Fp2 | 0.80 | 0.10 | 0.446 |
ð SUPRA-SECTION 1: EEG ANALYSIS
Analysis of motor cortex activity during finger tapping task using 4 good EEG channels (C3, C4, F3, F4).
1.0 EEG Power Spectral Density (Preprocessed)
1.0.1 Left Hemisphere PSD by Condition
Electrodes: FC1, FC5, C3, CP1, CP5 (left motor cortex cluster)
1.0.2 Right Hemisphere PSD by Condition
Electrodes: FC2, FC6, C4, CP2, CP6 (right motor cortex cluster)
1.0.3 Time-Frequency Maps (Most Informative)
Time-Frequency Representation (TFR) showing power changes across time and frequency for motor cortex channels C3 and C4.
Expected patterns:
- Blue patch (ERD): Power decrease in 8-30 Hz starting before movement onset (motor planning) and continuing during execution
- Red patch (ERS): Power increase in Beta (~20 Hz) after movement ends (motor inhibition/rebound)
- Contralateral effect: C3 shows stronger ERD for RIGHT hand, C4 shows stronger ERD for LEFT hand
Color scale: Blue = desynchronization (ERD), Red = synchronization (ERS), White = no change from baseline
1.0.4 Contralateral ERD/ERS Timecourse
Classic motor cortex desynchronization: C3 desynchronizes during RIGHT hand movement (contralateral), C4 desynchronizes during LEFT hand movement (contralateral). Shows alpha (8-13 Hz) and beta (13-30 Hz) bands.
1.0.5 Contralateral ERD/ERS Spatial Distribution
Topographic maps showing ERD/ERS spatial distribution during task execution (2-4s after onset). Blue = desynchronization (ERD), Red = synchronization (ERS). Bottom row shows LEFT-RIGHT contrast highlighting contralateral effect.
Event-Related Desynchronization (ERD) Analysis
Analysis Channel: C3
| Metric | Value | Status |
|---|---|---|
| Alpha ERD (8-13 Hz) | -0.3% (p=0.0500) | â |
| Beta ERD (13-30 Hz) | -0.2% (p=0.0500) | â |
| Beta Rebound (post-task) | -0.0% | â |
Expected Patterns:
- Mu ERD: -20% to -40% during task (motor cortex activation)
- Beta ERD: -30% to -50% during movement
- Beta rebound: +10% to +30% after task cessation
ð§ SUPRA-SECTION 2: fNIRS ANALYSIS
Analysis of hemodynamic response in motor cortex during finger tapping task.
fNIRS Quality Metrics Summary
| Metric | Value |
|---|---|
| Total Channels | 42 |
| Bad Channels | 12 |
| Mean SCI | 0.000 |
| Mean Saturation % | 0.05% |
| Mean Cardiac Power | 1.195 |
| Mean CV % | 1.78% |
Bad Channels Details
| Channel | Reason |
|---|---|
| S1_D1 760 | ['Low SCI (0.28 < 0.75)'] |
| S1_D1 850 | ['Low SCI (0.28 < 0.75)'] |
| S2_D2 760 | ['Low SCI (0.72 < 0.75)'] |
| S2_D2 850 | ['Low SCI (0.72 < 0.75)'] |
| S7_D1 760 | ['Low SCI (0.50 < 0.75)'] |
| S7_D1 850 | ['Low SCI (0.50 < 0.75)'] |
| S8_D2 760 | ['Low SCI (0.34 < 0.75)'] |
| S8_D2 850 | ['Low SCI (0.34 < 0.75)'] |
| S5_D3 760 | ['Low SCI (0.71 < 0.75)'] |
| S5_D3 850 | ['Low SCI (0.71 < 0.75)'] |
| S8_D4 760 | ['Low SCI (0.54 < 0.75)'] |
| S8_D4 850 | ['Low SCI (0.54 < 0.75)'] |
Hemodynamic Response Function (HRF) Validation
Analysis Channel: S6_D4 hbo
| Metric | Value | Status |
|---|---|---|
| HbO Onset Time | 0.0s | â |
| Time-to-Peak | 0.0s | â |
| Plateau Amplitude | 0.00 ΞM (p=0.0500) | â |
| Trial Consistency | r=0.80 | â |
Expected Patterns:
- HbO onset: 2-3s post-stimulus (neurovascular delay)
- Time-to-peak: 4-8s for brief stimuli
- Plateau amplitude: Significantly positive (p < 0.05)
- Trial consistency: r > 0.5 indicates reliable response
ð SUPRA-SECTION 3: EEG + fNIRS (MULTIMODAL COUPLING)
Analysis of neurovascular coupling between EEG and fNIRS signals.
Neurovascular Coupling Analysis
| Metric | Value | Status |
|---|---|---|
| Maximum Correlation | r=nan | â |
| Optimal Lag | -28.0s | â |
Expected Patterns:
- Negative lag: EEG changes precede HbO changes by 2-5s
- Correlation strength: r > 0.4 indicates adequate coupling
- Interpretation: Neural activity drives hemodynamic response
====================================================================== VALIDATION CRITERIA ASSESSMENT ====================================================================== EEG Analysis (Motor Cortex Activation): ---------------------------------------------------------------------- [FAIL] Alpha ERD significant: -0.3% (p=0.0500) [FAIL] Beta ERD significant: -0.2% (p=0.0500) [FAIL] Beta rebound observed: -0.0% post-task EEG Summary: 0/3 criteria met fNIRS Analysis (Hemodynamic Response): ---------------------------------------------------------------------- [FAIL] HbO onset detected: 0.0s (expected: 2-3s) [FAIL] Time-to-peak plausible: 0.0s (expected: 4-8s) [FAIL] Plateau amplitude significant: 0.00 ΞM (p=0.0500) [PASS] Trial consistency acceptable: r=0.80 (threshold: >0.5) fNIRS Summary: 1/4 criteria met Neurovascular Coupling: ---------------------------------------------------------------------- [PASS] EEG precedes fNIRS: lag=-28.0s (negative expected) [FAIL] Correlation strength adequate: r=nan (threshold: >0.4) Coupling Summary: 1/2 criteria met ====================================================================== OVERALL: 2/9 criteria met (22%) ====================================================================== â RECOMMENDATION: Validation failed. Major issues detected. Significant problems with: - EEG signal quality or task engagement - fNIRS optode coupling or hemodynamic response Recommend troubleshooting before proceeding. Diagnostic Suggestions: ---------------------------------------------------------------------- âĒ Alpha ERD not significant: Check C3 electrode placement, verify subject engaged in task, consider longer task duration âĒ Beta ERD not significant: Verify movement execution, check for excessive muscle artifacts âĒ HbO onset not detected: Check optode coupling (SCI), verify task timing, consider motion artifacts âĒ Plateau amplitude not significant: Check optode placement, verify task difficulty sufficient to elicit response âĒ Weak coupling correlation: May indicate poor signal quality in either EEG or fNIRS, or weak task-related activation
Pipeline Configuration
Configuration parameters used for this analysis:
{
"eeg_enabled": true,
"fnirs_enabled": true,
"eeg_channels_of_interest": [
"C3",
"C4"
],
"trials_per_condition": 12,
"task_duration_sec": 15.0,
"rest_duration_sec": 15.0
}